To test for Trousseau phenomenon, a healthcare provider may inflate a blood pressure cuff on the upper arm above the systolic blood pressure for a few minutes. This obstructs blood flow to the forearm, leading to ischemia (reduced blood supply) and neuromuscular irritability in individuals with hypocalcemia. In a positive Trousseau sign, the patient may experience involuntary muscle contractions, particularly flexion of the wrist and metacarpophalangeal joints, which is known as carpopedal spasm.